題目

Hemoptysis + Hematuria =  **Wegner's vasculitis (Granulomatosis with polyangiitis**): 侵犯上呼吸道(鼻竇)、下呼吸道(肺部)和腎臟(腎絲球炎)  \- URT: epistaxis, chronic rhinosinusitis, septal perforation, saddle nose \- Lung: cough, dyspnea, hemoptysis  \- Kidney: RPGN, hematuria  Serology: c-ANCA & anti-GBM antibody  D) for chronic rhinosinusitis **Goodpasture syndrome**: GN + pulmonary hemorrhage \-- There is a subgroup of patients that is double-positive for both ANCA and anti-GBM \-- Kidney biopsy is the gold standard for diagnosis