Tibolone
\-- Estrogen agonist
\-- HRT for Postmenopause
Biphosphonate
\-- Inhibit bone resorption
\*路人補充
Tibolone可以用在緩解女性停經症候群之不適,其仿單裡禁忌症有提到若有VTE(靜脈血栓栓塞)風險者不得使用,高風險群包括懷孕、長時間固定不動、嚴重肥胖、SLE等
tibolone仿單連結->https://www.ktgh.com.tw/Public/tbDrug/201809071726217055.pdf

但也有文章在討論tibolone會不會造成SLE flare up
\->文章連結: https://www.maturitas.org/article/S0378-5122(09)00006-1/fulltext
\->文章conclusion: In patients with inactive or stable SLE, **the short-term use of tibolone did not significantly affect the frequency of flares. In addition, tibolone was well tolerated and effective to control hypoestrogenism related symptoms in SLE patients.**
不知道這題想考的是哪個?
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