題目

(A) Koilocyte = HPV;  Herpes = multinucleated giant cell of Tzanck smear (B) Call-Exner bodies = Granulosa cell tumor (C) Birbeck granules = Langerhans cell histiocytoses;  yolk sac tumor = Schiller-Duval body (D) Reinke crystalloid = Leydig cell tumor A) Koilocyte：源自squamous epithelial cell，代表HPV 感染，產生以下四個病變特 徵：核腫大、膜不規則、核濃染、核周圍有白暈(perinuclear halo)。差不多就跟荷包 蛋很像。而Herpes 感染的病理特徵為：Vesicles with multinucleated giant cells containing intranuclear inclusions surrounded by clear halos. (B) Call-Exner bodies: small eosinophilic fluid-filled spaces between granulosa cells. 代表 Granulosa cell tumors (C) Birbeck granules: rod shaped or "tennis-racket" cytoplasmic organelles with a central linear density and a striated appearance. 代表Langerhans cell histiocytoses (D) Reinke crystalloid: rod-shaped crystal-like structures with pointed or rounded ends present in the interstitial cells of the testis (Leydig cells) and ovary.